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In Print: Last Week's Pharmacogenomics Papers of Note

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Circulating microRNA-21 as noninvasive predictive biomarker for response in cancer immunotherapy.
Wang Z, Han J, Cui Y, et al.
Med Hypotheses. 2013 May 10 [Epub ahead of print]


Processed B-Type Natriuretic Peptide Is a Biomarker of Postinterventional Restenosis in Ischemic Heart Disease.
Fujimoto H, Suzuki T, Aizawa K, et al.
Clin Chem. 2013 May 13. [Epub ahead of print]


Challenges and limitations in interpretation of systematic reviews: Making sense of clopidogrel and CYP2C19 pharmacogenetics.
Sorich MJ, Polasek TM, Wiese MD.
Clin Pharmacol Ther. 2013 May 13. [Epub ahead of print]


Platform comparisons for identification of breast cancers with a BRCA-like copy number profile.
Schouten PC, van Dyk E, Braaf LM, et al.
Breast Cancer Res Treat. 2013 May 14. [Epub ahead of print]


Evaluation of Heart Failure Biomarker Tests: A Survey of Statistical Considerations.
De A, Meier K, Tang R, Li M, et al.
J Cardiovasc Transl Res. 2013 May 14. [Epub ahead of print]


Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.
Innocenti F, Ramírez J, Obel J, et al.
Pharmacogenet Genomics. 2013 May 10. [Epub ahead of print]


Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS).
Beech RD, Leffert JJ, Lin A, et al.
Pharmacogenomics J. 2013 May 14. [Epub ahead of print]


A microarray-based gene expression analysis to identify diagnostic biomarkers for unknown primary cancer.
Kurahashi I, Fujita Y, Arao T, et al.
PLoS One. 2013 May 9;8(5):e63249.


Pharmacogenetics in clinical practice: how far have we come and where are we going?
Johnson JA.
Pharmacogenomics. 2013 May;14(7):835-43.


Lung cancer in never-smokers. Does smoking history matter in the era of molecular diagnostics and targeted therapy?
Ou SH.
J Clin Pathol. 2013 May 9. [Epub ahead of print]


The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer.
Eklöf V, Wikberg ML, Edin S, et al.
Br J Cancer. 2013 May 9. [Epub ahead of print]

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.