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Pairings: Mar 31, 2010

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Integrated Diagnostics, a personalized diagnostics company founded by Leroy Hood, announced the appointment of Albert Luderer as its first CEO. Luderer was previously president and CEO of BioTrove, a molecular biological tools company acquired by Life Technologies in December.

Before BioTrove, Luderer held leadership positions at several firms, including Light Sciences and bioMérieux. Luderer also had a hand in the creation of Siemens Diagnostics. He holds a PhD from Rutgers University where he was a National Science Foundation predoctoral fellow.

Integrated Diagnostics, raised $30 Million in Series A funding in September, is a newly formed company that uses genomic and proteomic techniques to personalize treatment by identifying blood proteins synthesized in the organ of interest.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.