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Kinaxo, Roche Dx Sign Second Collaboration

NEW YORK (GenomeWeb News) – Kinaxo Biotechnologies said today that it will collaborate with Roche Diagnostics to support Roche’s development of new targeted treatment-related technologies.

Under the agreement, which is the second collaboration between the companies, Kinaxo will use its PhosphoScout phosphoproteomics technology to support targeted treatment development.

PhosphoScout enables identification of regulated protein phosphorylation sites, and does not require antibodies for detection, enabling phosphoproteome analysis across signaling pathways, Martinsried, Germany-based Kinaxo said.

Kinaxo’s chemical proteomics and quantitative phosphoproteomics tools support drug mode-of-action analysis, drug repositioning, cellular target profiling, and target deconvolution, according to the company.

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.