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HTG Molecular Secures $16M Debt Facility

NEW YORK (GenomeWeb) – HTG Molecular Diagnostics today announced the closing of a growth capital term loan facility for up to $16 million with Silicon Valley Bank and Oxford Finance.

HTG said it drew $11 million of the funding at the initial closing.

In February, the Tucson, Ariz.-based firm closed a Series E preferred stock offering for an undisclosed amount. In a statement today, HTG CEO TJ Johnson said, "Together with the capital raised through recent equity offerings, the debt facility with SVB/Oxford provides HTG the funding needed to pursue several operating initiatives, including key research and development programs and strategic sales and marketing expansion."

The RNA-based testing firm launched its first next-generation sequencing-based assay in June, which targets and sequences 2,275 microRNAs using proprietary nuclease protection probe technology. Johnson told In Sequence at the time that the panel is the first of several NGS-based assays in HTG's pipeline and that the company eventually will move into DNA-based assays.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.