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Originally published May 7.

Over the past several years there has been a major shift in cancer diagnostics from systems based on physical and histological findings to methods that assess and treat tumors based on the presence of distinct, targetable genomic mutations. A primary example of this shift is lung cancer, a disease that was long viewed as monolithic and with few treatment options, but now is known to have many molecular subtypes and genetic tests that can match patients with those subtypes to treatments.

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