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Empire Genomics Licenses Biomarker from Emory University for Multiple Myeloma CDx

NEW YORK (GenomeWeb News) – Empire Genomics said today that it has acquired the exclusive license to a genomic biomarker from Emory University for the development of a molecular diagnostic test for determining which therapies may be most suitable for specific patients with multiple myeloma.

A phase II biomarker-driven clinical trial is being conducted using the technology to validate its ability to predict outcomes of new generations of drugs for the blood cell cancer, Empire Genomics said.

The Buffalo, NY-based firm is commercializing the test, and plans to use the biomarker in lymphoma patients as part of its effort to support and accelerate clinical trials and create cancer companion diagnostics. It anticipates launching the test through clinical laboratories in early 2013.

"Developing a clinically validated multiple myeloma cancer theranostic assay with informative data will represent a major breakthrough in improving disease management," Leon Bernal-Mizrachi, an assistant professor of hematology and medical oncology at the Emory University School of Medicine, said in a statement. "It would fulfill an unmet medical need to help patients with multiple myeloma better plan treatment options that will help produce the best outcomes."

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.