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In Brief This Week: Life Technologies; SG Biofuels; Ambry Genetics; Wheat Genome; Gen-Probe; AnaSpec

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Life Technologies and SG Biofuels announced together they have completed sequencing the Jatropha curcas genome to 100-fold coverage, using Life Tech's SOLiD 4 platform. The sequence will be used go generate a high quality Japtropha reference genome, which will be compared to SG Biofuels' germplasm library of more than 6,000 Jatropha genotypes, in order to identify molecular markers and trait genes "to accelerate development of elite cultivars with vastly superior yields and profitability," Life Tech said in a statement.


Ambry Genetics has purchased Illumina's HiSeq 2000 sequencing platform and received the first 510(k) approved Illumina BeadXpress system for genotyping. In a statement, Ambry said the HiSeq will allow it to run large projects for its customers at lower costs and faster turn-around time.


UK researchers released the first sequence coverage of the wheat genome. The sequences comprise five read-throughs of a reference variety of wheat, and gives access to 95 percent of all wheat germs.


Gen-Probe said that its Prodesse ProFast+ assay has received its CE Mark, allowing the test to be sold in Europe. The assay received FDA clearance in July. The test simultaneously detects and differentiates three common influenza A viruses — seasonal A/H1, season A/H3, and 2009 H1N1.


Interprise Brasil will has entered a non-exclusive worldwide collaboration to distribute AnaSpec's catalog and custom products in Brazil. Financial terms were not disclosed.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.