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NEW YORK – Researchers in the UK, the US, and Belgium have found that while the SARS-CoV-2 virus has undergone significant changes in its evolutionary history, those changes likely occurred while the virus was still found mainly in bats, resulting in a "relatively generalist" virus that was capable of infecting humans without the need for an intermediary species.

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Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.