NEW YORK (GenomeWeb) — Mayo Clinic researchers have demonstrated in a new study that measuring CYP2D6 status from breast tumor tissue can be inaccurate due to loss of heterozygosity in the CYP2D6 gene region. The authors argue that this may be the reason why some large studies have failed to show a connection between CYP2D6 genotype and response to tamoxifen.

The group published the study online this month in the Journal of the National Cancer Institute.

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Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.