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Large-Scale Proteomic Studies Identify Proteins Linked to Diabetes, Metabolic Syndrome
The two studies, published separately in Cell Reports Medicine, used affinity-based and mass spec platforms to analyze thousands of blood samples.
In particular, Thermo Fisher's decision to embrace the approach with its new Orbitrap Astral platform further cements DIA's place in the mainstream.
Cedars Sinai Team Develops Method for Quantitative Label-Free Proteomics Without LC Separation
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Such direct infusion mass spec workflows are niche within proteomics, but sample handling and ion mobility advances could drive future adoption.
While Orbitraps continue to be a popular option, new time-of-flight mass spec technologies have made significant inroads with proteomics researchers.
Several major vendors released mass spectrometry platforms and accessories aimed at the growing market for spatial analysis of small molecules and proteins.