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Sep 09, 2015

UCSD Researchers Win Grant to Develop Extracellular RNA Biomarker Panel for Glioma

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The funding coincides with publication of reports from the Extracellular RNA Consortium outlining growth and challenges in exosomal RNA-based diagnostics.

Feb 19, 2015

Regulus Plans for New Clinical Trials, Third Drug Candidate in '15

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The company provided updates for its hepatitis C and Alport syndrome candidates, which are both set to enter Phase II testing this year.

Feb 09, 2015

New Data Shows Higher Dose of Regulus HCV Drug Offers Better Viral Load Reductions

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The data also point to viral load reductions regardless of disease genotype, extent of patient liver fibrosis, or failure with other treatments.

Feb 02, 2015

Regulus Hits Milestone in Biogen Idec microRNA Biomarker Deal

Regulus said it was able to develop its miRNA extraction and profiling technology to meet the quality specifications set out by its partner.

Dec 03, 2014

Alnylam Publishes Paper on Development of GalNAc Conjugate Delivery Technology

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The delivery approach has gained traction in recent years and is being explored by a number of RNA drug firms.

Nov 24, 2014

Data Point to Regulus Alport Drug Use in Late-stage Disease, Other Kidney Diseases

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The data show that RG-012 can enhance the effect of Sanofi's kidney protectant ramipril and suggest the microRNA drug might have use in other chronic kidney diseases.

Nov 06, 2014

Wall Street in October Proves Tumultuous for Four RNAi/microRNA Shops

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NEW YORK (GenomeWeb) — October was a turbulent month on Wall Street for several key RNAi/microRNA players, with two companies — Regulus Therapeutics and Alnylam Pharmaceuticals — seeing major gains on encouraging clinical data and two others — Arrowhead Research and Tekmira Pharmaceuticals — taki

Nov 06, 2014

Regulus Weighs Dual Development Track for HCV Drug

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NEW YORK (GenomeWeb) — Buoyed by positive Phase I data on its microRNA-targeting hepatitis C drug RG-101, Regulus Therapeutics is aiming to begin Phase II testing of the dr

Nov 06, 2014

Regulus Closes $103.5M Stock Offering

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NEW YORK (GenomeWeb) — Regulus Therapeutics announced this week that it has closed its previously announced public stock offering, raising $103.5 million through the transaction.

Oct 30, 2014

Regulus to Raise $90M in Stock Offering

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NEW YORK (GenomeWeb) — Regulus Therapeutics this week announced that it had priced its previously announced public offering of roughly 5.3 million shares of its common stock at $17 apiece, valuing the transaction at about $90 million.

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The Scan

Yep, Couple of Concerns There

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

Told to Pause

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

Passing on Trauma, Maybe

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

This Week in PNAS

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.

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