Regeneron Rare Variants in G Protein-Coupled Receptor Gene May Provide Protection From Obesity The Regeneron Pharmaceuticals-led team also said that inhibiting the gene could represent a potential therapeutic strategy for obesity. Investigational CRISPR Therapy Shows Efficacy Against Transthyretin Amyloidosis in Phase I Study The therapy works by reducing serum concentration of misfolded transthyretin protein, which leads to the life-threatening disease. UK Biobank Collaborating With Biopharmas to Profile Plasma Proteome of 53K Subjects Led by a group of 10 biopharmaceutical firms, the project will use Olink's proteomic technology to look at participants' plasma levels of roughly 1,500 proteins. UCLA Health, Regeneron Collaborate on Whole-Exome Sequencing The Regeneron Genetics Center will provide whole-exome sequencing for 150,000 patients who will be able to opt-in to receive actionable results. COVID-19 Human Genetic Studies Presented at ASHG Point to Disease Susceptibility, Severity Loci Results of three studies, which had overlapping findings, were presented at the American Society of Human Genetics 2020 virtual meeting on Wednesday. Oct 21, 2020 UK Biobank Exomes Reveal Loss-of-Function Variants, Potential Disease Ties Jul 7, 2020 Exome Analysis of Southwestern American Indians Highlights Metabolic Disease-Linked Variants Jun 9, 2020 DNAnexus Lands $100M in New Financing May 11, 2020 Regeneron, Colorado Center for Personalized Medicine Ink Genomic Research Partnership Jun 14, 2019 Regeneron, Mayo Ink Pact to Sequence, Genotype 100K Patient Samples Apr 19, 2019 Active Celiac Disease Processes Informed by Intestinal Expression Comparison Mar 25, 2019 UK Biobank to Make Whole-Genome Sequencing Data on 500K-Sample Repository Publicly Available Premium Apr 24, 2018 Loss-of-Function, Truncating Variants in UK Biobank Data Point to New Drug Targets Mar 22, 2018 Researchers Find Gene Variant That Protects Against Chronic Liver Disease Mar 19, 2018 Global Gene, Regeneron Genetic Center Form Sequencing Alliance Feb 13, 2018 Regeneron Genetics Center Partners With Multiple Sclerosis Non-Profit on Sequencing Project Jan 8, 2018 Regeneron Partners With AbbVie, Alnylam, AstraZeneca, Biogen, Pfizer to Sequence UK Biobank Samples Nov 16, 2017 Regeneron Says Large-Scale Human Genetics Starting to Generate New Drug Targets Premium Nov 16, 2017 Geisinger Experience Implementing Precision Medicine Spurs New Effort to Help Others Do the Same Premium Aug 30, 2017 Formulatrix Readying Next-Gen Digital PCR Platform for Market Premium May 25, 2017 Targeting ANGPTL3 Could Lead to Development of Heart Disease Therapies Mar 23, 2017 GlaxoSmithKline, Regeneron Partner to Sequence Entire UK Biobank Feb 8, 2017 Penn Medicine Gets $3M From Pharma Consortium for Diabetic Kidney Disease Study Jan 31, 2017 Indivumed, Regeneron Ink Cancer Sample, Data Deal Dec 22, 2016 Analysis of Nearly 51,000 Geisinger Patient Exomes, EHRs Reveal Actionable Variants, Drug Targets Load More Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.