Regeneron Clonal Hematopoiesis Linked to Common, Rare Genetic Variants Analyzing almost 628,400 exome sequences, researchers found common and rare variants corresponding with different forms of clonal hematopoiesis of indeterminate potential. Mexican Population Genetics Studies Highlighted at ASHG Meeting Premium Recently compiled Mexican population genetic datasets reveal historical population structures, predict complex traits, and improve bioinformatic tools. Mount Sinai Million Health Discoveries Program Represents New Ground for Partner Regeneron Premium While Regeneron has more than 100 other sequencing collaborations, including with All of Us and UK Biobank, none approaches the scale of its new plans with Mount Sinai Health System. Mount Sinai, Regeneron Launch Sequencing Project to Augment Genetics-Based Precision Medicine The program, named Mount Sinai Million Health Discoveries Program, aims to enroll 1 million Mount Sinai patients over a five-year period for sequencing. Exome Sequencing Study Uncovers Rare Variants in Gene Protecting Against Liver Disease The findings of the study, which was funded by Regeneron Pharmaceuticals, suggest a new treatment for conditions like nonalcoholic steatohepatitis (NASH). Jul 12, 2022 Ultima Genomics, Regeneron Pharmaceuticals Ink Development Agreement Dec 2, 2021 Variant Identified in Amish Population Appears to Protect From Cardiovascular Disease Oct 19, 2021 Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Jul 1, 2021 Rare Variants in G Protein-Coupled Receptor Gene May Provide Protection From Obesity Jun 28, 2021 Investigational CRISPR Therapy Shows Efficacy Against Transthyretin Amyloidosis in Phase I Study Dec 7, 2020 UK Biobank Collaborating With Biopharmas to Profile Plasma Proteome of 53K Subjects Nov 16, 2020 UCLA Health, Regeneron Collaborate on Whole-Exome Sequencing Oct 29, 2020 COVID-19 Human Genetic Studies Presented at ASHG Point to Disease Susceptibility, Severity Loci Oct 21, 2020 UK Biobank Exomes Reveal Loss-of-Function Variants, Potential Disease Ties Jul 7, 2020 Exome Analysis of Southwestern American Indians Highlights Metabolic Disease-Linked Variants Jun 9, 2020 DNAnexus Lands $100M in New Financing May 11, 2020 Regeneron, Colorado Center for Personalized Medicine Ink Genomic Research Partnership Jun 14, 2019 Regeneron, Mayo Ink Pact to Sequence, Genotype 100K Patient Samples Apr 19, 2019 Active Celiac Disease Processes Informed by Intestinal Expression Comparison Mar 25, 2019 UK Biobank to Make Whole-Genome Sequencing Data on 500K-Sample Repository Publicly Available Premium Apr 24, 2018 Loss-of-Function, Truncating Variants in UK Biobank Data Point to New Drug Targets Mar 22, 2018 Researchers Find Gene Variant That Protects Against Chronic Liver Disease Mar 19, 2018 Global Gene, Regeneron Genetic Center Form Sequencing Alliance Feb 13, 2018 Regeneron Genetics Center Partners With Multiple Sclerosis Non-Profit on Sequencing Project Jan 8, 2018 Regeneron Partners With AbbVie, Alnylam, AstraZeneca, Biogen, Pfizer to Sequence UK Biobank Samples Load More Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.