Regeneron Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Regeneron Genetics Center researchers and their colleagues identified a number of protective gene-trait associations from the UK Biobank dataset. CRISPR and mRNA Together Time magazine reports on the use of mRNA to deliver CRISPR machinery. Rare Variants in G Protein-Coupled Receptor Gene May Provide Protection From Obesity The Regeneron Pharmaceuticals-led team also said that inhibiting the gene could represent a potential therapeutic strategy for obesity. Investigational CRISPR Therapy Shows Efficacy Against Transthyretin Amyloidosis in Phase I Study The therapy works by reducing serum concentration of misfolded transthyretin protein, which leads to the life-threatening disease. UK Biobank Collaborating With Biopharmas to Profile Plasma Proteome of 53K Subjects Led by a group of 10 biopharmaceutical firms, the project will use Olink's proteomic technology to look at participants' plasma levels of roughly 1,500 proteins. Oct 29, 2020 COVID-19 Human Genetic Studies Presented at ASHG Point to Disease Susceptibility, Severity Loci Oct 21, 2020 UK Biobank Exomes Reveal Loss-of-Function Variants, Potential Disease Ties Jul 7, 2020 Exome Analysis of Southwestern American Indians Highlights Metabolic Disease-Linked Variants Jun 9, 2020 DNAnexus Lands $100M in New Financing May 11, 2020 Regeneron, Colorado Center for Personalized Medicine Ink Genomic Research Partnership Jun 14, 2019 Regeneron, Mayo Ink Pact to Sequence, Genotype 100K Patient Samples Apr 19, 2019 Active Celiac Disease Processes Informed by Intestinal Expression Comparison Mar 25, 2019 UK Biobank to Make Whole-Genome Sequencing Data on 500K-Sample Repository Publicly Available Premium Apr 24, 2018 Loss-of-Function, Truncating Variants in UK Biobank Data Point to New Drug Targets Mar 22, 2018 Researchers Find Gene Variant That Protects Against Chronic Liver Disease Mar 19, 2018 Global Gene, Regeneron Genetic Center Form Sequencing Alliance Feb 13, 2018 Regeneron Genetics Center Partners With Multiple Sclerosis Non-Profit on Sequencing Project Jan 8, 2018 Regeneron Partners With AbbVie, Alnylam, AstraZeneca, Biogen, Pfizer to Sequence UK Biobank Samples Nov 16, 2017 Regeneron Says Large-Scale Human Genetics Starting to Generate New Drug Targets Premium Nov 16, 2017 Geisinger Experience Implementing Precision Medicine Spurs New Effort to Help Others Do the Same Premium Aug 30, 2017 Formulatrix Readying Next-Gen Digital PCR Platform for Market Premium May 25, 2017 Targeting ANGPTL3 Could Lead to Development of Heart Disease Therapies Mar 23, 2017 GlaxoSmithKline, Regeneron Partner to Sequence Entire UK Biobank Feb 8, 2017 Penn Medicine Gets $3M From Pharma Consortium for Diabetic Kidney Disease Study Jan 31, 2017 Indivumed, Regeneron Ink Cancer Sample, Data Deal Load More Breaking News Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Cystic Fibrosis Sinus Infections Involve Microbes With Shifting Evolution Patterns Molecular Assemblies Wins $256K NIH Phase I SBIR Grant to Develop Enzymatic DNA Synthesis Vibrent Health, VCU Partner to Offer Twin Research Platform Castle Biosciences Acquires Cernostics for up to $80M Princess Margaret Cancer Centre, Inivata Partner on Clinical Liquid Biopsy Studies The Scan Could Mix It Up The US Food and Drug Administration is considering a plan that would allow for the mixing-and-matching of SARS-CoV-2 vaccines and boosters, the New York Times says. Closest to the Dog New Scientist reports that extinct Japanese wolf appears to be the closest known wild relative of dogs. Offer to Come Back The Knoxville News Sentinel reports that the University of Tennessee is offering Anming Hu, a professor who was acquitted of charges that he hid ties to China, his position back. PNAS Papers on Myeloid Differentiation MicroRNAs, Urinary Exosomes, Maize Domestication In PNAS this week: role of microRNAs in myeloid differentiation, exosomes in urine, and more.