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Proteome Sciences

The new guidelines mark the second publication in recent months to suggest that protein biomarkers be integrated into current definitions of Alzheimer's disease, though the new proposal explicitly calls for protein biomarkers to be used only in research settings.

Under the deal, which follows on a similar 2009 agreement between the firms, Proteome Sciences will provide Takeda with mass spec-based assays for the discovery and validation of protein biomarkers tied to various undisclosed diseases.

Takeda will use the PS Biomarker Services for the development of mass spectrometry-based assays for disease-related proteins.

The agreement calls for Proteome Sciences to quantify plasma levels of the nine proteins in its AD-TMT-SRM panel, which uses multiple-reaction-monitoring mass spectrometry and the company's Tandem Mass Tagging technology.

Under a deal announced today, Proteome Sciences will measure candidate biomarkers for Alzheimer's disease for Eisai.

Movers & Shakers


Kenneth Fang, Alf Lindberg, Catherin Derasp

Proteome Sciences will provide biomarker analysis services for the J&J company.

Proteome Sciences will provide Icon's clients with its expertise in single-reaction monitoring mass spectrometry, said a company official. The partners' first joint project is the development of an SRM assay measuring a biomarker for an unnamed drugmaker.

The firms plan to offer an integrated biomarker services solution for pharmaceutical candidate development.

Movers & Shakers


Gregory Critchfield, Ian Pike, Rainer Metternich


The former commissioner of the FDA has returned to the venture capital firm New Enterprise Associates as a special partner on the healthcare investment team.

Astronauts have edited yeast genes on the International Space Station in an experiment designed to show how cells repair themselves in space.

Emory University has found that two of its researchers failed to divulge they had received funds from China, according to the Atlanta Journal-Constitution.

In Science this week: influence of the nuclear genome on human mitochondrial DNA, and more.