Proteome Sciences Plasma Proteomics Prioritizes Throughput but Depth Could Prove a Limitation Premium High-throughput workflows promise to boost discovery efforts, but some question whether they currently deliver the necessary depth of coverage. Proteome Sciences' TMTcalibrator Could Enable Deep Plasma Proteomic Analysis Premium While the company has offered the technique for more than a decade it has recently begun exploring its suitability for larger-scale plasma proteomic studies. PNNL Team Devises High-Throughput Single-Cell Proteomics Workflow Premium The approach uses miniaturized sample prep and isobaric tagging and can identify up to 2,300 proteins in single cells and analyze around 100 cells per day. Tandem Mass Tag Usage Could Benefit From New Methods, Expanded Applications Premium New instrumentation, reagents, and methods, as well as increasing interest in small and single-cell samples, could prove a boon for the technology. UW-Madison Team Develops Workflow for 24-Plex Proteomic Experiments Premium The method combines stable isotope dimethyl labeling with DiLeu isobaric tagging and allows multiplexing of up to 24 samples in a single mass spec experiment. Mar 14, 2018 Princeton Team Develops New Isobaric Tagging Method Premium Feb 3, 2017 Researchers Apply Mass Spec to Single-Cell Proteomics Premium Oct 31, 2016 Proteome Sciences Raises £3.3M Oct 6, 2016 Proteome Sciences Investigating Variety of Phospho-Tau Forms as Alzheimer's Markers Premium Sep 19, 2016 Proteome Sciences Narrows Business Focus Under New Leadership Premium Jun 23, 2015 Proteome Sciences Conditionally Raises £2.5M Feb 3, 2015 Proteome Sciences Signs Deal to Join MedBiomix Network Nov 14, 2014 Proteome Sciences Lowers 2014 Guidance, Cites Delay of Contracts Premium Oct 17, 2014 People in the News: Martin Diggle Premium Oct 3, 2014 Proteome Sciences Posts 12 Percent Decline in Revenue in H1 Premium Sep 26, 2014 Proteome Sciences Scores $2M from Genting TauRx for Alzheimer's Plasma Protein Biomarker Work Premium Sep 25, 2014 Proteome Sciences Inks $2M Deal with Genting TauRx for Alzheimer's Biomarker Work Jul 11, 2014 Proteome Sciences, King's College Team IDs Plasma Protein Markers Linked to Alzheimer's Premium Jul 7, 2014 People in the News: Rao Mulpuri, Roger McDowell Premium May 30, 2014 Proteome Sciences Reports 86 Percent Rise in 2013 Revenues Premium Apr 4, 2014 Proteome Sciences Uses Sysquant for Phosphoproteomic Study of Clinical Pancreatic Cancer Samples Premium Mar 7, 2014 People in the News: Subha Madhavan, Anthony Walker Premium Feb 24, 2014 Proteome Sciences Eyes $8.3M Raise Nov 22, 2013 Proteome Sciences and Kings College ID Protein Markers for Stratifying Liver Cancer Patients Premium Nov 22, 2013 People in the News: Frederick Sanger, Premal Shah, Jedd Levine Premium Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.