Proteome Sciences In Brief This Week: Illumina, Thermo Fisher, Tempus, Bionano Genomics, Danaher, More News items for the week of Aug. 14, 2023 Plasma Proteomics Prioritizes Throughput but Depth Could Prove a Limitation Premium High-throughput workflows promise to boost discovery efforts, but some question whether they currently deliver the necessary depth of coverage. Proteome Sciences' TMTcalibrator Could Enable Deep Plasma Proteomic Analysis Premium While the company has offered the technique for more than a decade it has recently begun exploring its suitability for larger-scale plasma proteomic studies. PNNL Team Devises High-Throughput Single-Cell Proteomics Workflow Premium The approach uses miniaturized sample prep and isobaric tagging and can identify up to 2,300 proteins in single cells and analyze around 100 cells per day. Tandem Mass Tag Usage Could Benefit From New Methods, Expanded Applications Premium New instrumentation, reagents, and methods, as well as increasing interest in small and single-cell samples, could prove a boon for the technology. Aug 31, 2018 UW-Madison Team Develops Workflow for 24-Plex Proteomic Experiments Premium Mar 14, 2018 Princeton Team Develops New Isobaric Tagging Method Premium Feb 3, 2017 Researchers Apply Mass Spec to Single-Cell Proteomics Premium Oct 31, 2016 Proteome Sciences Raises £3.3M Oct 6, 2016 Proteome Sciences Investigating Variety of Phospho-Tau Forms as Alzheimer's Markers Premium Sep 19, 2016 Proteome Sciences Narrows Business Focus Under New Leadership Premium Jun 23, 2015 Proteome Sciences Conditionally Raises £2.5M Feb 3, 2015 Proteome Sciences Signs Deal to Join MedBiomix Network Nov 14, 2014 Proteome Sciences Lowers 2014 Guidance, Cites Delay of Contracts Premium Oct 17, 2014 People in the News: Martin Diggle Premium Oct 3, 2014 Proteome Sciences Posts 12 Percent Decline in Revenue in H1 Premium Sep 26, 2014 Proteome Sciences Scores $2M from Genting TauRx for Alzheimer's Plasma Protein Biomarker Work Premium Sep 25, 2014 Proteome Sciences Inks $2M Deal with Genting TauRx for Alzheimer's Biomarker Work Jul 11, 2014 Proteome Sciences, King's College Team IDs Plasma Protein Markers Linked to Alzheimer's Premium Jul 7, 2014 People in the News: Rao Mulpuri, Roger McDowell Premium May 30, 2014 Proteome Sciences Reports 86 Percent Rise in 2013 Revenues Premium Apr 4, 2014 Proteome Sciences Uses Sysquant for Phosphoproteomic Study of Clinical Pancreatic Cancer Samples Premium Mar 7, 2014 People in the News: Subha Madhavan, Anthony Walker Premium Feb 24, 2014 Proteome Sciences Eyes $8.3M Raise Nov 22, 2013 Proteome Sciences and Kings College ID Protein Markers for Stratifying Liver Cancer Patients Premium Load More Breaking News Verily Awarded CDC Contract for Wastewater Surveillance Genomic Health to Pay $32.5M to Resolve Cancer Test False Claims Allegations by DOJ Vela Diagnostics Inks Japan Distribution Agreement for HIV-1 Drug Resistance Tests Coronary Artery Calcification Contributors, Potential Drug Targets Found in Cross-Ancestry GWAS Max Planck Team Uses Spatial Single-Cell Proteomics Method to Analyze Hepatocyte Heterogeneity The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.