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Paired Ends: Apr 27, 2010

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Patrick Hurban, Louise Grant, Ardy Arianpour, Katherine Richardson, Stéphane Bancel, Daniel Kastner

In a motion to a libel, slander, and breach of contract suit that Transgenomic filed in February, Power3 said that Transgenomic could not "plead fraud" because it failed to allege that any claims made by Power3 were false.

The lawsuit, filed this week in US District Court in Nebraska, stems from a deal signed last year to develop and commercialize Power3's biomarker tests for neurodegenerative diseases.

Following the release of its Q4 and full-year financial results, Transgenomic updated investors on how its COLD-PCR technology may drive future revenues through diagnostic kit sales and testing services, and said that it has signed contracts with three pharma companies to explore applications for the technology.

The molecular diagnostics firm also posted a profit versus a loss a year ago.

Transgenomic has claimed in a suit that Power3 has wrongly terminated a licensing deal between the firms, while engaging in fraud and slander.

The company plans to develop and sell an autism risk test for children with older siblings who have already been diagnosed.

Clinical Data is planning to submit a new drug application to the US Food and Drug Administration for its investigational depression drug vilazodone in the current quarter. However, due to unfavorable Phase III results on a response biomarker, the company will not be submitting its NDA with a companion test.

Sales of its Familion genetic tests were a primary driver of revenue growth for the quarter.

Duke researchers and the SAEC will use whole-genome sequencing to identify and validate rare gene variants associated with clozapine-induced immunological response.

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The Economist reports that it is increasingly easier to analyze the metabolites people give off, potentially revealing personal information about them.

The Los Angeles Times reports that only a third of California students meet the state's new science standards.

A controversial paper on the gender gap in science has been corrected, according to BuzzFeed News.

In Science this week: evidence of interbreeding between the ancestors of West Africans and an unknown archaic human, and more.