Plexxikon Plexxikon Taps Certara's Software for Drug Discovery Data Analysis Premium This week, Certara said that Plexxikon has selected its D360 software solution to support data access and analysis for its drug discovery projects. FDA Official Says Personalized Medicine Regulation Taking Shape Following Zelboraf, Xalkori Success Premium By Turna Ray Plexxikon Launching Phase I/II Trial for PLX3397 in AML Patients with Flt3 Mutations Premium Originally published Dec. 12. Large Kinase Datasets from Fox Chase, Ambit Teams Offer Insights into Inhibitor Selectivity Premium By Adam Bonislawski Two papers published in the current edition of Nature Biotechnology add significantly to the publicly available data on the specificity of kinase inhibitors. UK's NICE Cites Lack of Response Markers for BMS' Yervoy as Factor in Negative Recommendation Premium Originally published Oct. 18. By Turna Ray Sep 28, 2011 Roche Says FDA-Approved BRAF Test Is Better Than Sanger-based LDTs, but is it Enough to Sway Labs? Premium Sep 14, 2011 FDA's Reorganization of Oncology Office May Be Good for PGx-Guided Drugs Premium Aug 17, 2011 FDA Simultaneously Approves Roche/Plexxikon's Drug, Companion Dx for BRAF-Mutated Melanoma Premium Jun 15, 2011 Exome Sequencing IDs Druggable BRAF Mutation in 47 HCL Patients Premium Jun 8, 2011 Roche, BMS Hope to Improve Outcomes in BRAF-Mutated Melanoma Patients with Dual Treatment Regimen Premium May 18, 2011 Plexxikon, Roche File Rx/Dx Application for PLX4032, Cobas Mutation Test in Metastatic Melanoma Premium Jan 19, 2011 Genentech Says PGx-Guided Melanoma Drug Meets Primary Endpoints in Phase III Trial Premium Sep 1, 2010 NEJM Paper Yields Positive Efficacy Results for Roche/Plexxikon's PGx Melanoma Drug Premium Sep 23, 2009 Roche Offers Rx/Dx Pipeline Update at UBS Life Sciences Conference Premium Breaking News KSL Pulse Scientific to Distribute Lucira Health Home COVID-19, Flu Molecular Test in Canada NTU-Singapore Launches S$160M Institute for Digital Molecular Analytics and Science New Products Posted to GenomeWeb: Thermo Fisher, Adaptive Biotech, Qiagen, Dolomite Bio, More People in the News at Oncocyte, PrognomiQ, BillionToOne, Haystack Oncology, More In Brief This Week: BC Platforms, Thermo Fisher Scientific, Jumpcode Genomics, More The Scan Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine. Study Uncovers Genetic Mutation in Childhood Glaucoma A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma. Gene Co-Expression Database for Humans, Model Organisms Gets Update GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says. New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.