Plexxikon Plexxikon Taps Certara's Software for Drug Discovery Data Analysis Premium This week, Certara said that Plexxikon has selected its D360 software solution to support data access and analysis for its drug discovery projects. FDA Official Says Personalized Medicine Regulation Taking Shape Following Zelboraf, Xalkori Success Premium By Turna Ray Plexxikon Launching Phase I/II Trial for PLX3397 in AML Patients with Flt3 Mutations Premium Originally published Dec. 12. Large Kinase Datasets from Fox Chase, Ambit Teams Offer Insights into Inhibitor Selectivity Premium By Adam Bonislawski Two papers published in the current edition of Nature Biotechnology add significantly to the publicly available data on the specificity of kinase inhibitors. UK's NICE Cites Lack of Response Markers for BMS' Yervoy as Factor in Negative Recommendation Premium Originally published Oct. 18. By Turna Ray Sep 28, 2011 Roche Says FDA-Approved BRAF Test Is Better Than Sanger-based LDTs, but is it Enough to Sway Labs? Premium Sep 14, 2011 FDA's Reorganization of Oncology Office May Be Good for PGx-Guided Drugs Premium Aug 17, 2011 FDA Simultaneously Approves Roche/Plexxikon's Drug, Companion Dx for BRAF-Mutated Melanoma Premium Jun 15, 2011 Exome Sequencing IDs Druggable BRAF Mutation in 47 HCL Patients Premium Jun 8, 2011 Roche, BMS Hope to Improve Outcomes in BRAF-Mutated Melanoma Patients with Dual Treatment Regimen Premium May 18, 2011 Plexxikon, Roche File Rx/Dx Application for PLX4032, Cobas Mutation Test in Metastatic Melanoma Premium Jan 19, 2011 Genentech Says PGx-Guided Melanoma Drug Meets Primary Endpoints in Phase III Trial Premium Sep 1, 2010 NEJM Paper Yields Positive Efficacy Results for Roche/Plexxikon's PGx Melanoma Drug Premium Sep 23, 2009 Roche Offers Rx/Dx Pipeline Update at UBS Life Sciences Conference Premium Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.