The contract was awarded as part of the VA's Precision Oncology Program, which aims to provide advanced clinical care and generate cancer biomarker data.
The company, which first signed on to provide services to the VA's Million Veteran Program in 2013, will provide the department with 34,000 more genomes.
Researchers compared three open source annotation tools, and also looked at correspondence with public databases, identifying a number of stumbling blocks.
The company has been working with the VA since 2013, when it it received a contract to provide sequencing and data analysis for enrollees in the Million Veteran Program.
The companies have signed a letter of intent to offer Personalis' next-generation tumor sequencing and interpretation technology to customers in Canada.
The partners will provide comprehensive clinical genomic testing for tumor profiling and inherited genetic disease at LSU Health New Orleans' Precision Medicine Program.
Compared to commercial exome kits and whole-genome sequencing, the firm's test had improved coverage in medically interpretable genes and the 56 ACMG genes.
In April, Butte became director of UCSF's Institute for Computational Health Sciences and executive director of clinical informatics for UC Health Sciences and Services.
