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Pacific Biosciences

PacBio Bioinformatics Focusing on Pipelines to Support Long-Read Sequencing Data
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The most recent software, Paraphase, produces "mini haplotypes" rather than counting copy number variations to identify variants linked to rare diseases.

Johns Hopkins Team Using Long-Read Sequencing to Crack Genetic Code of Pancreatic Cancer
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Funded by the Lustgarten Foundation, the researchers plan to analyze 400-plus pancreatic cancer samples to study the genetic changes linked to the disease.

To Q40 and Beyond: Sequencing's Accuracy Revolution is Happening Now
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New, more accurate methods are posing problems for the NGS ecosystem as researchers rethink the concept of accuracy altogether.

Chinese University of Hong Kong, Take2 Sue Pacific Biosciences Over DNA Methylation Detection Tech

The Hong Kong-based plaintiffs alleged that PacBio has copied their method of calling methylated bases using quirks of the PacBio sequencing method.

NHGRI's Verkko Algorithm Automates Telomere-to-Telomere Genome Assembly, With Limitations
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By augmenting PacBio HiFi sequencing with Oxford Nanopore ultralong reads, Verkko produced complete assemblies of 20 of the 46 human chromosomes.

Feb 16, 2023

Pacific Biosciences Q4 Revenues Fall 24 Percent

Feb 13, 2023

AGBT Sessions Shine Spotlight on Long-Read Sequencing
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Feb 13, 2023

Ewing Sarcoma Risk Locus Analysis Sheds Light on Cancer's Formation

Feb 10, 2023

AGBT: Pacific Biosciences Offers More Info on Onso Short-Read Sequencer Performance, Pricing

Feb 3, 2023

All of Us Researchers Make Case for Long Reads in Population Sequencing
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Feb 2, 2023

UBS Initiates Coverage of 10X Genomics, PacBio, Akoya Biosciences, NanoString Technologies

Jan 25, 2023

Pacific Biosciences to Raise $175M in Public Stock Offering

Jan 12, 2023

Pacific Biosciences Provides Updates on Platforms, Contracts at JP Morgan Conference

Jan 9, 2023

Preliminary Earnings Roundup: NanoString Technologies, SomaLogic, Pacific Biosciences, More

Jan 5, 2023

Sequencing Instrument Launches in 2022 Portend Heated Competition
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Nov 16, 2022

Pacific Biosciences Says More Sequencers in Development Pipeline, Outlines Future Growth Plans
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Nov 8, 2022

Pacific Biosciences Announces Revio Preorders as Q3 Revenues Dip 7 Percent

Nov 4, 2022

People in the News at Pacific Biosciences, Personalis, Epic Sciences, Cytek Biosciences, More

Nov 1, 2022

GenomeWeb Top 40 up 3 Percent in October After Two Months of Losses

Oct 26, 2022

Pacific Biosciences Reveals Follow-up Sequencer to Sequel II, Timeline for Short-Read Platform
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Oct 21, 2022

New Products Posted to GenomeWeb: Pacific Biosciences, Twist Bioscience, Beckman Coulter, More

Oct 21, 2022

In Brief This Week: Pacific Biosciences, Pierian, PerkinElmer, Ginkgo Bioworks, More

Oct 20, 2022

Human Pangenome Reference Consortium Develops 'Semi-Automated' Diploid Genome Assembly Method
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Sep 22, 2022

Northeastern University Researchers Develop New Type of Zero-Mode Waveguide for Sequencing
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Sep 21, 2022

Improved Nanopore Basecalling Models Help Reduce Sequencing Errors in Telomeres
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Breaking News
The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.