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Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts

 

CEO: Gordon Sanghera

Website: www.nanoporetech.com

Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

The researchers are working to improve the protocol and are in discussions with Oxford Nanopore Technologies to make it available to users. 

Interviews with leading UK scientists revealed apprehension about losing access to European funding, limitations on freedom of movement, and an exodus of biotechs to the EU.

There is significant interest in technologies that provide long-range genomic information, but only among a subset of users.

The agency is sending an Oxford Nanopore MinIon to the International Space Station to determine if the technology's microfluidic system can work in microgravity.

At a user meeting in London this week, Chief Technology Officer Clive Brown introduced the SmidgIon and a number of other technology developments, as well as a new synthetic biology spinoff.

Two groups independently developed statistical methods that can call methylation marks from nanopore sequence data. 

Breaching the Barrier

Whole-genome sequencing advances hold promise for medicine, the Financial Times reports.

In a letter to the International Trade Commission, Oxford claimed that the suit is an attempt by Illumina to expand its monopoly in the DNA sequencing market.

The new R9 pore, which the company has licensed from VIB in Belgium and plans to release for the MinIon and the PromethIon, is based on the E. coli CsgG nanopore.

Almost Unicorn

Market research analysis firm Beauhurst says Oxford Nanopore is growing fast and highly valued.

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The General Data Protection Regulation has slowed some data sharing with non-European researchers as they find ways to comply with the law, ScienceInsider reports.

A bioethicist from Abertay University uses a utilitarian approach to justify genetically modifying the human germline, the BBC reports.

The US has upgraded its network of public health labs to provide whole-genome sequencing to track antibiotic-resistant bacteria, Quartz reports.

In Science this week: approach to visualize 3D genome structure in single cells, RNA interference knockdown screens to examine genetic origins of beetle horns and insect wings,  and more.