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Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts

 

CEO: Gordon Sanghera

Website: www.nanoporetech.com

Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

The US ITC has ruled that Oxford Nanopore's products do not infringe on single-molecule sequencing-related patents held by PacBio. 

Clive Brown, the company's chief technology officer, provided an update on the firm's business and talked about new products and planned improvements.

 

In Nature this week: nanopore sequencing and assembly human genome, method to reduce CRISPR off-target effects, and more.

Such Long Sequences

Researchers have used a portable nanopore sequencer to sequence and assemble a human reference genome.

The researchers plan to develop a clinical test to monitor CML patients in remission for the BCR-ABL1 rearrangement. 

In Nucleic Acids Research this week: tool to identify bacterial plasmid sequences, long-read sequencing of Saccharomyces cerevisiae strain, and more.

More than a third of NGS users plan to purchase a new sequencing system within a year, according to the survey, conducted by GenomeWeb and investment bank William Blair. 

Shrink It Down

Portable DNA sequencers are being used in wider range of locations, the Economist reports.

Japanese researchers developing the method highlighted its ability to accurately and rapidly diagnose different strains of malaria in resource-limited endemic regions. 

The company said that several companies in China are installing the GridIon X5 sequencing platform for in-house and service work.

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In PLOS this week: preconception carrier screening program results, comparative genomics-based analysis of Elizabethkingia meningoseptica, and more.

Canadian regulators are beginning to share information from new drug studies, Undark reports.

In a column at the Dallas Morning News, the Stanley Medical Research Institute's E. Fuller Torrey says the Human Genome Project hasn't delivered on promised results.

Researchers explore a possible genetic cause for some cases of sudden infant death syndrome, KOMO News reports.