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Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts


CEO: Gordon Sanghera


Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

The company will partner exclusively with Oxford University to develop "revolutionary products" for molecular analysis from research done in Bayley's lab, including the development of methods for the direct sequencing of single-stranded DNA.

Paired Ends: Aug 3, 2010


Daniel Turner, Elizabeth Brady, Emily Winn-Deen, Melina Cimler, Tristan Orpin, Terry Pizzie, Ajay Bansal, John Curson, Ken Prokuski, Lewis Shuster, Stephen McLean

The team's next step is to use the graphene as not only the membrane, but also as the electrodes, and to slow down the DNA so they can read each individual base as it passes through the pore.

The UK firm's lead technology uses nanopores to measure electrical currents of molecules as they interact with the nanopores, and then identifies the molecules based on the current.

Oxford Nanopore, which has been developing a real-time label-free single-molecule DNA sequencing technology as its lead application, plans to use part of the new investment to develop its platform for protein analysis.

The firm has raised nearly $80 million since its inception. Funds will be used to accelerate development of its sequencing technology.

The researchers applied a salt gradient across the nanopore, enabling them to use about 10,000 times less starting DNA than previous versions of the method.

Paired Ends: Sep 1, 2009


Michael Snyder, Jim McDonald

The firm's staff has grown from 25 in early 2008 to more than 60 to date, including informaticians, scientists, and engineers.

Paired Ends: Apr 28, 2009


Hagan Bayley, Detlef Weigel, Todd Smith, Michael Sadowsky, Catalina Lopez-Correa, Garry Merry


In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Science reports a new US defense bill would establish two groups aimed at combating foreign influence on research. 

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.