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Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts

 

CEO: Gordon Sanghera

Website: www.nanoporetech.com

Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

As part of a course this fall, 20 undergraduate and graduate students used the MinIon in two hands-on "hackathon" sequencing projects.

The consortium, a group formed by a number of participants in Oxford Nanopore's MinIon early-access program (MAP), plans to conduct a series of projects. 

The researchers detected a number of known structural variants from cancer cell lines in a background of wild-type sequence, using mixtures of PCR amplicons.

Beam the MinIon Up

NASA plans to test whether DNA sequencing studies can be conducted in microgravity.

The study demonstrated the efficacy of using the Oxford Nanopore MinIon and a bespoke computational pipeline to perform metagenomics testing of viral infections in patients. 

Using MinIon sequence data, they assembled the genomes of two bacterial isolates after culturing them for two weeks in a chip submerged in a stream.

The goal is to develop a test that can identify the pathogen involved and predict antibiotic susceptibility within six hours of taking a urine sample.

At The Atlantic, Ed Yong reports on the MinION's use to track Ebola in Africa.

In a paper in Nature Nanotechnology, the scientists demonstrate parallel measurements from many nanopores with single-base resolution, though not yet sequencing.

While the MinIon could generate influenza genome data in a clinically relevant timeframe, discrepancies in the sequence suggest it may not yet be ready for diagnostic use.

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Researchers have developed a robotic lab assistant, the Verge reports.

CBC News reports Canada's Supreme Court is to rule on the constitutionality of the country's genetic non-discrimination law today.

The Associated Press reports the World Health Organization is sending experts to China to investigate the animal source of SARS-CoV-2.

In Science this week: atlas of affected cell populations in idiopathic pulmonary fibrosis, and more.