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Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts

 

CEO: Gordon Sanghera

Website: www.nanoporetech.com

Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

On its first mission, the MinION will sequence phage lambda, bacterial, and mouse DNA to demonstrate that sequencing in space is feasible.

Including the latest round, the company has raised £251 million in total.

The $75,000 deposit converts into credit for consumables and workflows once participants have accepted the instrument.

Over the last month, MinIon users have published new reports on rapid pathogen sequencing as well as RNA isoform analysis.

Two teams from Europe and the US took the Oxford MinIon sequencer to West Africa to sequence Ebola samples.

The researchers described in a pre-print publication a modified sample prep process that enabled them to increase read lengths to over 100 kb.

The firm will launch a new version of the MinIon in 2016 and plans early access for the PromethIon this year. It also previewed an automated sample preparation system called Voltrax.

A recent presentation at the Clinical Virology Symposium highlighted the potential of unbiased sequencing for diagnosing infectious disease.

For their initial project, the group performed 16S sequencing of a Tanzanian frog species, potentially identifying a new species.

To demonstrate the method, the researchers assembled a 3.6-mb bacterial genome into one contig with average accuracy of 99.99 percent.

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The University of California, Berkeley's Jennifer Doudna reflects at Science on the anniversary of the announcement of the birth of twin girls who underwent genome editing.

By studying its enamel proteome, researchers have found the ancient ape Gigantopithecus blacki belongs to a sister clade to that of orangutans.

Bloomberg Businessweek discusses genomics with BGI's Wang Jian.

In Science this week: researchers find transplanting the gut microbiome in mice affects physiology, and more.