Oxford Nanopore

Oxford Nanopore Technologies was founded in 2005 to develop an electronic, single molecule sensing system based on nanopore science. The company now has more than 250 employees from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialization. Oxford Nanopore's instruments — MinIon, PromethIon, and GridIon are adaptable for the analysis of DNA, RNA, proteins, small molecules and other types of molecule.

Oxford Nanopore Facts

 

CEO: Gordon Sanghera

Website: www.nanoporetech.com

Ticker symbol: Privately held

Headquarters: Oxford, UK

Number of employees: 250+

The companies have been embroiled in several lawsuits in the US and in Europe, accusing each other of patent infringement.

The company will use the funding to build a manufacturing facility, expand commercialization efforts, and develop new products.

Most customers are still in the very early stages of testing the device but said that data yield per flow cell has been continually increasing to nearly 100 gigabases.

At AGBT, researchers reported on progress made in generating megabase-long reads on the MinIon, as well as initial work doing direct RNA sequencing. 

The US ITC has ruled that Oxford Nanopore's products do not infringe on single-molecule sequencing-related patents held by PacBio. 

Clive Brown, the company's chief technology officer, provided an update on the firm's business and talked about new products and planned improvements.

 

This Week in Nature

In Nature this week: nanopore sequencing and assembly human genome, method to reduce CRISPR off-target effects, and more.

Such Long Sequences

Researchers have used a portable nanopore sequencer to sequence and assemble a human reference genome.

The researchers plan to develop a clinical test to monitor CML patients in remission for the BCR-ABL1 rearrangement. 

In Nucleic Acids Research this week: tool to identify bacterial plasmid sequences, long-read sequencing of Saccharomyces cerevisiae strain, and more.

Pages

A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.