OSI | GenomeWeb

OSI

LAS VEGAS — Despite some recent setbacks, including ones in the RNAi field, oligonucleotide therapeutics are still likely to become the third major drug-development platform alongside small molecules and biologics in a matter of a few years, according to Art Krieg, the former CSO

Following a positive recommendation from the EMA committee, the European Commission is expected to issue a decision in September regarding marketing Tarceva as a first-line treatment for EGFR-mutation-positive NSCLC.

In separate agreements, Roche has obtained a worldwide sub-license from Genzyme to develop the EGFR assay, and will collaborate with OSI Pharmaceuticals to develop the companion diagnostic.

OSI will have access to AVEO's tumor models, archives, and biomarkers and will also acquire non-exclusive access to AVEO's proprietary bioinformatics platform.

OSI officials this week said that the availability of a long-vacant biocampus, the presence of a nearby budding biocluster, the promise of tax breaks and other economic incentives — and discontent with leaders in its current home base in New York's Long Island region — persuaded it to bypass North Carolina and Pennsylvania in favor of the Westchester County site.

In PNAS this week: carbapenem resistance in Enterobacteriaceae, selection against educational attainment-linked variants, and more.

Technology Review points out that a new US presidential science advisor hasn't been selected.

Researchers find that blood tests might be able to help determine severity of a concussion, Wired reports.

President-elect Donald Trump considers other candidates for director of the National Institutes of Health, Nature News reports.