Novartis Becton Dickinson, Navigate BioPharma Collaborate on Flow Cytometry Companion Diagnostics Development The partners will offer their combined expertise to biopharma companies developing diagnostics and clinical decision-making tools. Industry Groups Form European Coalition to Push for Better Comprehensive Genomic Profiling Access A coalition of a trade group and drugmakers and diagnostics firms aims to share best practices and recommendations for better test reimbursement and uptake. Cell-Free DNA Sequencing Can Detect Clonal Hematopoiesis in Cancer Patients Researchers used the new technique on 4,324 plasma samples of cancer patients. NCCN Publishes First Guidelines for Pediatric Brain Cancer, Recommends Broad NGS Profiling The guidelines recognize the importance of molecular profiling in diagnosing, treating, and identifying clinical trial opportunities for children with high-grade gliomas. Rancho Biosciences Launches Single-Cell Data Science Consortium With Pharma Firms BMS, J&J, Novartis, and Vesalius will work with the bioinformatics firm to develop standards for creating and using single-cell datasets for drug discovery. Apr 13, 2022 Precision Cancer Consortium Launches With Bayer, GSK, Roche, Novartis as Founding Members Nov 11, 2021 Breast Cancer Study Shows Number of Mutated PIK3CA Alleles Affects Tumor Aggressiveness Jul 16, 2021 FDA Approves Foundation Medicine's Liquid Biopsy Test as CDx for Novartis' Tabrecta in NSCLC Feb 16, 2021 Circulating Tumor DNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases Jan 14, 2021 Invitae, Pharma Firms Partner to Develop Standard MRD Panel for AML Clinical Trials Dec 9, 2020 Nonprofit Friends of Cancer Research Launches Public-Private HRD Harmonization Project Oct 27, 2020 FDA Approves Foundation Medicine Liquid Biopsy Test as CDx for Three Targeted Therapies May 6, 2020 FDA Approves Novartis' Capmatinib, Foundation Medicine CDx for Metastatic NSCLC Dec 4, 2019 FDA Approves Foundation Medicine CDx for Novartis Breast Cancer Drug Piqray Nov 19, 2019 Double Mutations in PIK3CA Gene Increase Patient Sensitivity to Targeted Therapies, Study Finds Premium Nov 7, 2019 Colorectal Cancers Dial up Mutability in Response to Targeted Treatments Oct 21, 2019 SomaLogic Expands Agreement With Novartis Sep 23, 2019 Global Survey Reveals Suboptimal Molecular Testing Access in Lung Cancer Despite Broad Guidelines Premium Jun 18, 2019 Next-Generation Sequencing of Pediatric Cancer Patients Could Transform Treatment Paradigms Premium May 24, 2019 FDA Approves Qiagen's PIK3CA Test as Companion Test for Novartis Breast Cancer Drug Feb 14, 2019 AbCellera, Novartis Partner on Antibody Drug Discovery Dec 7, 2018 Novartis Drug Shows Promise in PIK3CA Mutated Breast Cancer, Potential Utility of ctDNA Testing Premium Dec 6, 2018 Qiagen to Develop Companion Dx for Novartis Breast Cancer Drug Nov 13, 2018 Health Canada Approves Two BCR-ABL Tests Oct 30, 2018 Precision Oncology Highlights From ESMO 2018 Load More Breaking News NanoString, A*Star, Next Level Genomics to Launch Spatial Biology Laboratory in Singapore FDA Approves Entrogen's RAS Mutation Detection Kit as CDx for Vectibix Cancer Predisposition Variants Increase Secondary Cancer Mortality Risk in Pediatric Survivors BostonGene, Johns Hopkins University Partner for Multiple Cancer Clinical Research Projects KromaTid, Noble Life Sciences Ink Distribution, OEM Agreement The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.