Merck Serono Nonprofit Friends of Cancer Research Launches Public-Private HRD Harmonization Project The consortium aims to harmonize the use of homologous recombination deficiency as a biomarker to guide certain treatment types in cancer patients. FDA Gives Guardant Health IDE Approval for Clinical Trial of Merck KGaA Cancer Drug Guardant is providing its Guardant 360 CDx test for a clinical trial of Merck's small molecule, c-Met kinase inhibitor called tepotinib. Illumina, Merck Serono to Develop Universal NGS-based Oncology Dx The collaboration adds to a similar agreement Illumina struck with AstraZeneca, Janssen Biotech, and Sanofi last year. Spanish Cancer Institute Using Sysmex Inostics, Merck Serono Blood Dx to Study mCRC Personalized Rx Premium Vall d'Hebron's Institute of Oncology will use the liquid biopsy-based OncoBEAM RAS test to research precision medicine approaches for metastatic colorectal cancer patients. Comparison Shows Life Tech CastPCR Provides Equivalent Results to Therascreen for KRAS Detection Premium The customizable PCR plates may also be less expensive than the FDA-approved Therascreen kits. Jun 3, 2014 Merck KGaA, Sysmex Inostics Partner on Development of CRC Biomarker Test Jul 17, 2013 Merck Enlists Life Tech to Develop Companion Test for Cancer Drug, Other Pipeline Opportunities Premium Jul 16, 2013 Life Tech Inks Companion Dx Alliance with Merck Serono Sep 7, 2012 Merck Serono Spinoff Quartz Bio to Offer Specialized Biomarker Analysis Services to Pharma Premium Sep 3, 2012 Merck Serono Spins Out Bioinformatics Firm Jul 11, 2012 Merck KGaA, MDxHealth Explore Personalized Rx Strategy for Glioblastoma Patients with Methylated MGMT Premium Jul 3, 2012 Merck Serono, Compugen Form Joint Venture to Develop Genomic Tests for Drug-Induced Toxicity Premium Jun 25, 2012 Merck Serono, Compugen Form Biomarker Discovery Firm May 2, 2012 Merck Serono Survey Finds Limited Test Access, High Costs a Barrier to Personalized Rx Adoption in UK Premium Jan 20, 2011 Lead Discovery Center, Merck Partner on Kinase Inhibitor Discovery Jun 9, 2010 ASCO Reviewer Advises Genotyping to Improve Success for MEK-Inhibiting Cancer Drugs Premium Jun 10, 2009 BioSeek Extends Merck Profiling Plan to 2012 Mar 30, 2009 BioRegion Real Estate: Mar 30, 2009 Premium Mar 25, 2009 Tech Transfer Tidbits: Mar 25, 2009 Premium Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.