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Lundbeck

Relationship of Sitting Bull Descendant Verified With Ancient DNA From Lock of Hair

Using an approach tailored to low-coverage ancient DNA data and distant relationships, researchers confirmed family ties between the leader and his great-grandson.

23andMe, Lundbeck, Milken Institute Partner on Depressive, Bipolar Disorders Study

The study will combine cognitive assessments with genetic data and survey responses to gain insights into the causes of these two mental health conditions.

UniQure, Collaborators Secure $3.2M Eurostar Grant for Huntington’s Disease Effort
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Dutch gene therapy firm UniQure and academic collaborators have been awarded a three-year grant worth €2.5 million ($3.2 million) from the European Commission to develop a treatment for Huntington’s disease that combines RNAi and gene replacement.

Pistoia Launches Phase Two of Sequence Services Project; Emphasizes NGS Data Analysis, Management
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Participating vendors are being asked to build fully functional platforms for next-generation sequence data storage and analysis.

Lundbeck, UMMS to Collaborate on RNAi Therapeutic for Huntington's Disease
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Although Lundbeck's foray into the RNAi drugs scene is modest compared with investments made by other pharmas, it comes at a time when many of those firms have put the brakes on their commitment to the approach.
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The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.