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Lundbeck

Relationship of Sitting Bull Descendant Verified With Ancient DNA From Lock of Hair

Using an approach tailored to low-coverage ancient DNA data and distant relationships, researchers confirmed family ties between the leader and his great-grandson.

23andMe, Lundbeck, Milken Institute Partner on Depressive, Bipolar Disorders Study

The study will combine cognitive assessments with genetic data and survey responses to gain insights into the causes of these two mental health conditions.

UniQure, Collaborators Secure $3.2M Eurostar Grant for Huntington’s Disease Effort
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Dutch gene therapy firm UniQure and academic collaborators have been awarded a three-year grant worth €2.5 million ($3.2 million) from the European Commission to develop a treatment for Huntington’s disease that combines RNAi and gene replacement.

Pistoia Launches Phase Two of Sequence Services Project; Emphasizes NGS Data Analysis, Management
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Participating vendors are being asked to build fully functional platforms for next-generation sequence data storage and analysis.

Lundbeck, UMMS to Collaborate on RNAi Therapeutic for Huntington's Disease
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Although Lundbeck's foray into the RNAi drugs scene is modest compared with investments made by other pharmas, it comes at a time when many of those firms have put the brakes on their commitment to the approach.
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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.