Kinexus Bioinformatics

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Decodon has released Delta2D 4.3

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Ensembl Genomes 10, Discovery Studio 3.1, KiNET-Antibody Microarray database

The open-access database contains more than 1.5 million measurements of the phosphorylation levels of 400 protein kinases and their targets in more than 2,000 tissue and cell specimens.

The data covers how 3,800 different inhibitors affect 172 kinases. The researchers grouped the proteins based both on sequence and pharmacological relationships and by their interactions with various compound chemotypes.

The algorithm, which was developed in collaboration with researchers in the Mathematics of Information Technology and Complex Systems groups at the University of British Columbia and Simon Fraser University, will allow Kinexus to do high-resolution mapping of an estimated 25 million kinase-substrate interactions, said a company official.

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Kinexus Bioinformatics, BioDiscovery

Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.