Researchers detected excess genetic risk and/or misclassification when profiling ClinVar variants in ACMG-59 and OrphaNet genes using genome and exome sequences.
Craig Venter and Human Longevity aim to uncover disease through sequencing and other tests to increase lifespans, CNBC says.
The team found that constrained regions of the noncoding genome are up to 52-fold enriched for known pathogenic variants as compared to unconstrained regions.
Craig Venter says his company has uncovered disease in people who otherwise appeared healthy, HealthcareITNews reports.
Researchers have argued that the facial prediction claims are overblown and serve Human Longevity's financial interests in proprietary genomic databases.
In PNAS this week: trait prediction algorithm, missense mutation linked to hearing loss, and more.
Using a new algorithm, JCVI and Human Longevity researchers revealed potential re-identification risks using trait prediction from genome sequences.
The companies are aiming to identify treatment-response biomarker signatures in patients with advanced melanoma.
In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.
University of California, San Diego, researchers have developed a gene drive to control a fruit-destroying fly.
A new study of a β-thalassemia gene therapy appears promising, according to NPR.
In Nature this week: hair color genes, hybridization between 13-year and 17-year cicadas, and more.
Futurism writes that gene doping could be the next generation of cheating in sports.