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Caribou Biosciences

In Brief This Week: Danaher, SeqLL, Yourgene Health, Thermo Fisher, Caribou Bio, More

News items for the week of Aug. 30, 2021.

Caribou Biosciences Files for $100M IPO

The company plans to use the proceeds from the filing to advance the development of its drug candidates and genome editing technologies.

Oxford Nanopore Licenses CRISPR-Cas9 IP From Caribou Biosciences for Targeted Nanopore Sequencing

The firm said CRISPR will enable targeted sequencing of long regions of interest that were previously only accessible with long-read whole-genome sequencing.

CRISPR Patent Pools Pop Up, But Participation Uncertain as IP Holders Continue Legal Battles
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As MPEG LA tries to complete its larger CRISPR IP patent pool, smaller license agreements continue and a mini-pool has emerged between key players.

CRISPR License Agreements Prohibit Misuse, but Enforcement is Challenging
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CRISPR technology has made its way around the world, but in the wake of the He Jiankui controversy, the industry is asking what recourse it has against misuse.

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The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.