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Biodesix

The funds will go toward commercialization of its VeriStrat test for non-small cell lung cancer and to support collaborations with biotechnology and pharmaceutical firms to develop companion diagnostics.

According to a document filed with the SEC, Biodesix has raised half of its goal of $20 million. Funds will be used to further commercialize its VeriStrat test.

EGFR has emerged as a primary area of interest in cancer research, with biopharmaceuticals like Imclone's Erbitux and Amgen's Vectibix targeting the protein, but its multiple isoforms have made it difficult to predict these drugs' effectiveness, said Yale professor Nita Maihle.

The patents cover the selection of non-small cell lung cancer patients, colorectal cancer patients, and head and neck cancer patients for treatment with drugs targeting the epidermal growth-factor receptor pathway.

Veristrat, a protein biomarker-based companion diagnostic for non-small cell lung cancer, launched commercially in May 2009.

The serum-based proteomics test is now available in all 50 states.

While the company continues clinical studies showing the utility of its proteomics-based VeriStrat test in predicting response to cancer therapies, it also is forging partnerships with pharma for use of the test.

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Leroy Hood, Samuel Broder, Mark Velleca, Paul Beresford, Dino DiCamillo

The funding will go toward ongoing commercialization efforts for VeriStrat, the company's protein biomarker-based companion diagnostic for non-small cell lung cancer.

The money will go toward ongoing commercialization of VeriStrat, a serum proteomic-based test to help guide treatment of patients with non-small cell lung cancer.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.