Amgen

Results from two GWAS studies suggest that 15-LO inhibitors could be a viable treatment for nasal polyps and chronic rhinosinusitis.

The firm is using collaborations to access the large, diverse cohorts it needs to support its goal of commercializing its SomaScan system as a clinical platform.

The companies will use Somalogic's SomaScan proteomic platform to measure levels of as many as 5,000 proteins in up to 40,000 of DeCode's patient samples.

A GWAS meta-analysis involving hundreds of thousands of cases and controls led to new and known gallstone disease-associated variants at 28 loci.

Genome-wide association and meta-analyses have uncovered a dozen ADHD-related loci, providing insights into its biology and overlap with other conditions.

At least some variants associated with benign prostatic hyperplasia appeared to contribute to PSA levels in the blood, independent of prostate cancer.

This Week in Nature

In Nature this week: genomic and other analyses suggest the plant used to make chocolate was domesticated earlier and in a different region than previously thought, and more.

The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway.

The team uncovered more than 200 sites in the human genome that were differentially methylated based on parent of origin, including areas linked to disease.

Privately owned Oxford Nanopore offers a range of tools and and instruments based on a proprietary nanopore-based DNA and RNA sequencing technology.

Pages

Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.