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People in the News: Rob Metcalf, Joanne Spadoro, Todd Laird, and David Dimmock

Rob Metcalf

NextGxDx has appointed Rob Metcalf as CEO. Most recently, Metcalf served as president and chief operating officer for Digital Reasoning. He has also held multiple positions with LexisNexis, including as vice president of global operations for the company's practice management division. Metcalf succeeds Founder Mark Harris, who will step down as CEO and serve as the company's chief innovation officer.

Joanne Spadoro

T2 Biosystems has appointed Joanne Spadoro as chief operating officer. She has served as a member of the company's scientific advisory board, and as an operational consultant. Prior to joining T2, Spadoro was the chief scientific officer and vice president of worldwide operations at Immucor and senior vice president at Roche.

Todd Laird and David Dimmock

Rady Children's Hospital-San Diego has appointed Todd Laird as chief operating officer and David Dimmock as medical director. Most recently, Laird has been an active investor and advisor to a portfolio of early-stage life science companies. He has also held a variety of global operations and commercial roles with various companies, including American Hospital Supply, Baxter International, GE Healthcare, and Life Technologies. Before joining Rady Children's, Dimmock worked as a clinician and his practice focused on the diagnosis of heritable disorders in children and adults, and the longer term care of patients with mitochondrial and metabolic disorders. He has also been the principal investigator for multiple industry sponsored studies evaluating novel therapeutics for these disorders.

For more recent items on executive appointments and promotions in the omics and molecular diagnostics industries, please see the People in the News page on our website.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.