Agilent Technologies AriaDx Real-Time PCR System
Agilent Technologies has launched the AriaDx Real-Time PCR System in territories recognizing the CE mark for in vitro diagnostics. The modular design of customer-changeable optics in the instrument enables laboratories to use AriaDx with just one optical cartridge, and add more as required, up to six in total. The touchscreen and accompanying analysis software incorporates customer-favored features from the Stratagene Mx series while further increasing and streamlining analysis capabilities, Agilent said. The platform can be used for assays detecting gene expression, allele discrimination, and genotyping, and it is compatible with existing fast chemistry-based assays that are DNA-binding and probe-based.
Roche Avenio Millisect System
Roche announced the commercial availability of the Avenio Millisect System, a tissue dissection instrument that utilizes an automated digitally assisted process to isolate clinically relevant cells from formalin-fixed paraffin-embedded tissue slides. The system is designed to address tissue dissection challenges in clinical labs where manual dissection lacks consistency and precision, and laser capture microscopy is cumbersome and costly, Roche said. Optimized to fit easily into a variety of clinical workflow configurations, the system allows precise and consistent recovery of regions of interest for molecular pathology, improving the results of diagnostic testing by reducing false negatives and allowing identification of additional potential therapeutic targets. The Avenio Millisect System is an IVD labeled medical device and is now available in the US and countries accepting the CE mark.
Synthego Modified Synthetic sgRNA Libraries for Arrayed Whole Human Genome CRISPR Screening
Synthego announced the availability of modified synthetic single guide RNA (sgRNA) libraries for arrayed whole human genome CRISPR screening. The arrayed libraries are delivered ready-to-screen and have comprehensive coverage of the human genome, with several guide RNAs selected per gene, using the latest algorithms to enhance knockout efficiency. This leads to superior screening capabilities over RNAi and CRISPR pooled libraries, enabling a better understanding of gene function and smarter identification of drug targets for complex diseases, the company said. The Synthego whole human genome library is available in gene families including the druggable genome, transcription factors, G-protein coupled receptors, kinases, and immunology and immuno-oncology targets, among others. This feature enables focused CRISPR screens, allowing hypothesis-driven gene targeting and running of simultaneous screens without overlap.
For a full list of the gene families visit: www.synthego.com/libraries
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