Clontech's Smart-Seq v4 Ultra Low Input RNA Kit for the Fluidigm C1 System
Fluidigm and Takara Bio subsidiary Clontech Laboratories have jointly launched the Smart-Seq v4 Ultra Low Input RNA kit for the Fluidigm C1 system. The kit is available for four and 10 integrated fluidic circuits, and allows for high-quality cDNA synthesis starting from 96 single cells that have been isolated and processed with the C1 system. Like Clontech's other Smart-Seq v4 products, this kit provides higher sensitivity, more accurate expression data for genes with high GC content, and higher yield of cDNA compared to existing chemistry, the company said.
Bio Rad's Droplet Digital PCR Multiplex Mutation Screening Kits
Bio-Rad has added five products to its Droplet Digital PCR (ddPCR) Multiplex Mutation Screening Kits. Each research-use only kit detects key actionable cancer mutations in certain genes — KRAS Q61, NRAS G12, NRAS G12/G13, NRAS Q61, and BRAF V600 — as well as the wild-type allele in a single reaction. The complete portfolio also includes a previously-launched KRAS G12/G13 screening kit. The kits are compatible with all of the firm's ddPCR systems. The Droplet Digital method minimizes the effects of inhibitory substances and the kits identify mutations present at allelic frequencies at or below 0.5 percent. This makes them ideal for use with formalin fixed, paraffin embedded tissue and liquid biopsy samples, the company said.
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