New England Biolabs Monarch DNA Purification Kits
New England Biolabs has launched the Monarch family of products for DNA purification. Kits are available for gel extraction, plasmid miniprep, and reaction cleanup. They have optimized protocols and buffer systems for robust DNA cleanup and purification of plasmid DNA, and a unique column design that allows for elution in smaller volumes and does not retain buffer, eliminating unwanted carryover contamination. Monarch kits are also designed to minimize environmental impact — they're packaged using responsibly sourced, recyclable materials, and 44 percent less plastic. Buffers and columns can also be purchased separately.
ArcherDx SureShot Triple Fusion-Positive NGS Control
ArcherDx, in partnership with Horizon Discovery Group, has launched the Archer SureShot ALK, RET, ROS1 Fusion Control to benchmark greater in gene fusion detection using Archer FusionPlex Panels. The reference control is composed of formalin-fixed paraffin-embedded curls of homogeneously mixed, precisely defined cell lines that contain EML4-ALK, CCDC6-RET, and SLC34A2-ROS1 fusions. SureShot negative controls are also available, containing 100 percent wild-type cells that carry no target-gene fusion.
Clontech Guide-it CRISPR/Cas9 Gesicle Production System
Clontech Laboratories, a subsidiary of Takara Bio, has launched the Guide-it CRISPR/Cas9 Gesicle Production System. The kit enables delivery of CRISPR/Cas9 genome editing systems via gesicles, cell-derived nanovesicles engineered with surface glycoproteins to help bind and fuse to a broad range of cell types. Gesicles contain and deliver the Cas9 protein complexed with the guide RNA targeting the genomic site of interest. The kit includes lyophilized Xfect Transfection Reagent, gesicle packaging mixes containing coding sequences for the nanovesicle-inducing glycoprotein, Cas9 endonuclease, CherryPicker red fluorescent protein, a pre-linearized vector for cloning target sgRNA, and A/C Heterodimerizer for gesicle loading.
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