Integrated DNA Technologies xGen Exome Research Panel
Integrated DNA Technologies has launched the xGen Exome Research Panel for insightful analysis of the human exome via next-generation sequencing. The panel includes a total of 429,826 probes that span 39 Mb of the human genome, providing deep uniform coverage of 19,363 genes. Each probe within the panel is individually synthesized and undergoes a rigorous manufacturing and quality-assessment process in accordance with GMP standards. Missing or truncated probes are identified by mass spectrometry and OD measurements, and are eliminated before pooling, providing a unique advantage over array-derived probe pools. The approach selects for full-length probes, enabling highly uniform coverage. Scientists using the xGen Exome Research Panel with xGen Lockdown Reagents and the optimized protocol can now obtain reliable and reproducible exome data in a single day, IDT said in a statement.
Admera Health CardioGxOne Panel
Admera Health has launched the CardioGxOne next-generation sequencing panel for inherited cardiovascular disease. Developed as a joint venture between Admera Health and Health in Code, the test detects genomic variations in 213 genes related to familial cardiovascular diseases, and is designed to detect the genetic causes of sudden death in young individuals and athletes, such as cardiomyopathies, long QT, and Marfan syndrome. CardioGxOne combines the genetic and clinical information of more than 85,000 individuals from a proprietary database with a comprehensive interpretive report that is reviewed by specialized cardiology geneticists, Admera said.
Sciex CESI 8000 Plus
Sciex has launched the CESI 8000 Plus, a next-generation CESI-MS platform. The new system enables multiple experiments to be generated from as little as 5 mL of starting material. Combining this capability with the multi-segment injection technology, users can process 10 experiments in the time it would normally take to process one, with less than 1 L of material consumed, Sciex said. The system is ideal for experiments with limited samples, including microdialysates, needle biopsies, FFPE archives, and rare circulating tumor cells; or where samples are highly toxic. In addition, the innovation of neutral capillary surfaces further reduces system flow to less than 10 nanoliters/min, the company said. The platform also delivers higher-resolution separations, improved ionization efficiency, and reduced ion suppression. Optional laser-induced fluorescence, diode-array, and selectable wavelength UV detector modules are available, enabling off-line method development.
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