SeraCare Life Sciences Seraseq Solid Tumor Mutation Mix
SeraCare Life Sciences' precision medicine unit has launched its first product, Seraseq Solid Tumor Mutation Mix – I(AF20), a biosynthetic reference material designed to evaluate the performance of next-generation sequencing-based tumor profiling assays. The research-use-only product contains a mixture of mutations in key oncogenes and tumor suppressor genes and is intended as a quality material for translational and disease research testing, SeraCare said. It also allows laboratories to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics parameters.
Asuragen Quantidex Pan Cancer Kit
Asuragen has launched the Quantidex Pan Cancer Kit, a next-generation sequencing oncology panel of 21 genes relevant to a diverse set of human cancers. The kit integrates reagents, controls, and a novel bioinformatics suite and is optimized to interrogate difficult sample types such as formalin-fixed, paraffin-embedded and fine-needle aspiration tissues, Asuragen said. More specifically, the kit contains reagents for pre-analytical DNA QC, sample quantification, multiplex PCR enrichment, dual-index barcoding, and library purification and quantification, the company said. The product is currently for research use only, Asuragen noted.
Transgenomic ICEme Kits
Transgenomic has launched its ICEme Mutation Enrichment Kits for cancer biomarker research. The kits are based on the company's ICE COLD-PCR technology, which preferentially enriches mutant DNA sequences in an excess of wild-type DNA through selective amplification of the mutant DNA. The company said the kits are customizable, and the initial menu includes 17 clinically relevant, actionable mutations that are associated with important cancers.
10X Genomics GemCode Platform
10X Genomics has started shipping the GemCode platform for generating long range genomic information from short read sequencing data. The platform consists of instrumentation, reagents, and software and generates so-called Linked-Reads that deliver haplotype phasing, structural variation, and other genomic information. GemCode, which requires 1 nanogram of input DNA, partitions arbitrarily long DNA molecules and prepares multiple barcoded sequencing libraries in parallel. 10X Genomics previewed the product earlier this year at the Advances in Genome Biology and Technology conference.
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