ArcherDx Archer Analysis
ArcherDx has released the new version of its Archer Analysis bioinformatics platform. The software supports automated sequence analysis and mutation detection from libraries created using Archer's FusionPlex RNA-based sequencing assays. The Analysis 3.2 product also supports analysis for libraries created from the firm's forthcoming Archer VariantPlex DNA sequencing assays. In addition, it provides mutation detection and reporting for somatic and germline mutations and copy number variations, along with gene fusions, SNPs, and indels.
The firm noted that Analysis 3.2 has also been integrated with the Archer Quiver Fusion Database, a mutation database of all published gene translocations.
Biodesix's GeneStrat Liquid Biopsy Lung Cancer Test
Biodesix has launched GeneStrat, a PCR-based liquid biopsy test for patients with advanced non-small cell lung cancer. The assay uses BioRad's droplet digital PCR to identify clinically actionable mutations in EGFR, KRAS, and BRAF in circulating tumor DNA, which are useful in guiding targeted therapy treatment decisions in NSCLC.
This includes the EGFR T790M mutation, which is a marker of resistance to anti-EGFR drugs. According to Biodesix, turaround time for the test is 72 hours.
New England Biolabs's NEBNext Library Quant Kit for Illumina
New England Biolabs has launched its NEBNext Library Quant Kit for Illumina, a qPCR-based kit for accurate next-generation sequencing library quantitation. It includes a concentrated Library Dilution Buffer and ROX, a reference dye used for normalization with some qPCR instruments. A single extension time is required for all libraries, regardless of insert size, said NEB.
Kapa Biosystems' KAPA Stranded RNA-Seq Kit with RiboErase
Kapa Biosystems has launched its KAPA Stranded RNA-Seq Kit with RiboErase. The kit uses a targeted enzymatic depletion method to remove ribosomal RNA and thereby improve sequencing efficiency, the firm said. It also provides an alternative to mRNA enrichment and allows for the analysis of exonic regions, precursor mRNAs, and long non-coding RNAs.
For more recently launched products and services, please see the New Products page on our website.