Cancer Genetics Focus::Myeloid
Cancer Genetics has introduced Focus::Myeloid, a comprehensive next-generation sequencing-based panel for the diagnosis, prognosis, and clinical management of myeloid cancer patients, including those with acute myeloid leukemia, myelodysplastic syndrome, and myeloproliferative neoplasms. Utilizing Illumina NGS, the panel assesses 54 clinically relevant genes. Sanger sequencing is performed to assess abnormalities in several additional genes to provide a precise evaluation of the genetic profile of each patient's cancer, the company said. Focus::Myeloid is performed in CGI's CLIA certified lab, and is available as an individual test and as part of the company's complete programs for AML, MDS, and MPN, which offer a comprehensive assessment of the molecular genetics of the cancer along with pathology and morphological information.
Qiagen Biomedical Genomics Workbench
Qiagen has launched the Biomedical Genomics Workbench, a bioinformatics platform that provides end-to-end and customizable analysis workflows for the discovery of biomarkers associated with hereditary disease and cancer. The new workbench replaces the existing CLC Cancer Research Workbench. Key features of the platform include dynamic 3D protein structure visualizations for functional impact assessment; new modules for high-sensitivity identification of copy number alterations, CHiP-seq analysis, and the detection of variation in whole-genome, -exome, and targeted amplicon sequencing and transcriptome data; and tools for differential gene expression analysis and restriction and cloning site mapping.
Swift Biosciences Accel-NGS Methyl-Seq DNA Library Kit for Illumina platforms
Swift Biosciences this month launched the Accel-NGS Methyl-Seq DNA Library Kit for Illumina platforms. The new kit uses Adaptase technology, which enables next-generation sequencing libraries to be made post-bisulfite treatment, allowing researchers to recover more of their input DNA and use 100-fold less input material compared to other commercially available products, the company said. The new approach also avoids the high bias inherent in random primer-based methods as the underlying technology ligates adapters in a sequence-independent manner, Swift said.
Thermo Fisher Applied Biosystems PowerUp SYBR Green PCR Master Mix
Thermo Fisher has launched the Applied Biosystems PowerUp SYBR Green PCR Master Mix, a pre-formulated, universal, 2X concentration master mix designed to improve the specificity and reproducibility of qPCR workflows. The mix contains proprietary Dual-Lock Taq DNA polymerase, which includes a combination of two hot-start mechanisms used to control Taq activation for increased specificity. The inclusion of UNG and dUTP enzymes also prevents previously amplified PCR products from contaminating subsequent qPCR reactions. The mix be used in either standard or fast cycling mode and is compatible with all qPCR instruments.
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