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In Brief This Week: Sequenom; Promega; Danaher; Agilent; Horizon Discovery; Silicon Biosystems; Warnex

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Sequenom this week said that the American Journal of Obstetrics and Gynecology has accepted for publication a manuscript that details the results of the firm's "locked-assay" study on its Trisomy 21 test. It did not provide a planned date for the article.

Promega has joined the United Nations Global Compact as part of a sustainability program the firm launched in 2009. Under the compact, firms must commit to supporting 10 universally accepted principles in the areas of human rights, labor, environment, and anti-corruption.

Danaher has raised the lower end of the range for its fourth-quarter and full-year guidance. The firm now expects earnings per share of between $.64 and $.66 for the fourth quarter, up from the previous range of between $.61 and $.66. Its full-year EPS guidance has been raised to between $2.28 and $2.30, up from between $2.25 and $2.30.

Agilent Technologies this week said that its foundation has awarded researchers at Princeton University's Lewis-Singler Institute for Integrative Genomics and the Center for Quantitative Biology with equipment valued at more than $800,000. The foundation provided its Thought Leader Award to David Botstein, who directs the center and colleagues. Among the equipment that the firm donated is a microfluidic liquid chromatography-on-a-chip system, a 1290 Infinity UHPLC system, and 6500 Series quadrupole time-of-flight mass spectrometry system.

Horizon Discovery said that it intends to provide training and open access to its rAAV Genesis human gene-editing platform for another 50 academic and non-profit research groups who join the firm's Genesis Gene Editing Consortium over the next five years. The expansion is part of Horizon's plan to generate at least 2,500 new X-Man models of cancer, neurodegenerative diseases, and cardiovascular disease.

Silicon Biosystems, an Italian firm that has developed a lab-on-a-chip technology for molecular and cell biology applications, has opened a US subsidiary in San Diego. It will focus on introducing the firm's DEPArray technology platform to the research and clinical diagnostics markets in North America.

Warnex this week said that it its Warnex Pro-DNA Services division in Thunder Bay, Ontario, has received accreditation from the American Society of Crime Lab Directors/Laboratory Accreditation Board – International for forensic science testing. The firm said the lab was specifically accredited in the categories of nuclear and mitochondrial DNA testing, relationship testing, and body fluid identification.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.