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In Brief This Week: Roche Molecular Diagnostics; Decode Genetics; Eurofins MWG Operon, Geospiza; Institut de Cancerologie Gustave Roussy; Genomics USA

NEW YORK (GenomeWeb News) – Roche Molecular Diagnostics this week said that its new Cobas p 630 Instrument has been launched with a CE Mark in Europe. The instrument is an automated, pre-analytical solution that is used with the firm's Amplilink 3.3 Series Software, which integrates the cobas p 630 with Roche's Cobas AmpliPrep Instruments and Cobas TaqMan Analyzers.

Decode Genetics has again raised the principal amount of a promissory note executed with Saga Investments. The firm said that the amount is now $3,820,000 and has a maturity date of Nov. 2, 2009. In early September, Decode initially executed the promissory note with Saga with a principal amount of $700,000, which had an interest rate of 8 percent per annum and was payable in full on Oct. 11, 2009. It has since increased the amount of the note several times.

Eurofins MWG Operon has selected Geospiza's GeneSifter Lab Edition software to manage its DNA sequencing systems, the firms said this week.

The Institut de Cancerologie Gustave Roussy (IGR) France announced today that its Genomic Center has been awarded ISO 9001 certification for quality management and compliance. IGR said that its center is the first academic Agilent-Certified Service Provider in the world to receive this certification. It noted that it also is a European Reference and Training Center for Agilent, running the complete portfolio of Agilent's microarray technologies.

Genomics USA said that it has been awarded a three-year, $2.52 million phase II continuation grant from the National Institute of Allergy and Infectious Diseases to support further development of its HLA chip for HLA typing for solid organ and stem cell transplantation. The Inverness, Ill.-based firm said that it also received a two-year, $600,000 phase I grant from NIAID to develop an AIDS chip.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.