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In Brief This Week: Novartis; Agilent; IntegraGen; Evotec, Apeiron

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Novartis this week said that it will invest more than $600 million over the next five years to expand its global research campus in Cambridge, Mass. The Cambridge site houses the Novartis Institutes for Biomedical Research, Novartis Molecular Diagnostics, Novartis Vaccines and Diagnostics, and the US office of Novartis Venture Funds.

The company expects the investment will include adding 300 jobs, however a company spokesperson declined to provide further details.

Agilent Technologies has opened a new instruments manufacturing facility in Singapore, the firm announced today. The new facility will produce the firm's liquid chromatography/mass spectrometry instruments for the global market.

French molecular diagnostics developer IntegraGen said this week that it will open a US subsidiary based in Cambridge, Mass, on Nov. 1. The new US base will support the firm's clinical research initiatives focused on identifying children at risk of autism. IntegraGen also conducts gene discovery research and provides genotyping services to the research community.

Evotec said this week that it will apply its expertise in cellular assay development in a collaboration with Apeiron Biologics to identify potential targets for pain therapies.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.