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In Brief This Week: MDxHealth; Agendia; Pressure Biosciences; and More

NEW YORK (GenomeWeb) – MDxHealth announced this week that its ConfirmMDx for Prostate Cancer test has been granted a Category I MAAA Current Procedural Terminology (CPT) code by the American Medical Association. The CPT code will help the company with reimbursement for the test, MDxHealth said.


Agendia said this week that its MammaPrint 70-Gene Breast Cancer Recurrence Assay has also been granted a Category I, MAAA CPT code by the AMA.


Pressure BioSciences said this week that it has closed a $2 million line of credit with an unnamed investor. The investor has purchased a promissory note in the aggregate principal amount of up to $2 million due and payable either on Oct. 28, 2017 or on the seventh business day after the closing of a qualified offering, whichever comes first. The company has also received its initial $250,000 advance pursuant to the note, and has issued a five-year common stock purchase warrant to the investor to buy 625,000 shares of the company's common stock at an exercise price of $.40 per share.


Caris Life Sciences announced this week that it has designated the West Virginia University Cancer Institute as a center of excellence site in the Caris Centers of Excellence for Precision Medicine Network. The WVU Cancer Institute will now actively participate in the development of standards of care and best practices for integrating and utilizing molecular profiling in oncology practice, while also working toward adoption and patient access to personalized medicine in the clinic. The Institute will also have access to Caris' multiple-technology tumor profiling service.


Researchers at NRGene and the Kazusa DNA Research Institute in Japan have sequenced for the first time the genome of a commercially grown strawberry. The octoploid, heterozygous strawberry genome was assembled using reads produced on Illumina sequencing technology and assembled with NRGene's cloud-based DeNovoMAGIC 3.0 software package.


Fulgent Genetics reported this week that its third quarter revenues rose 72 percent to $5 million from $2.9 million a year ago. The company completed its initial public offering of 4.2 million shares of common stock on Oct. 4, raising approximately $36.3 million. The firm recorded a net loss of $1 million for the quarter, and ended Q3 with $8.2 million in cash. For Q4, Fulgent expects $5.8 million to $6.2 million in revenues, representing a 107 percent increase at the midpoint over Q4 2015.


ADS Biotec announced this week that it has acquired Genial Laboratory Automation, the instruments division of Genial Genetics. The acquisition strengthens ADS' product portfolio, the company said.

 

In Brief This Week is a selection of news items that may be of interest to our readers but had not previously appeared on the GenomeWeb site.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.