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In Brief This Week: Integromics, Ingenuity Systems; Source BioScience; Caliper; CLC Bio; Ontario Genomics Institute

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Integromics and Ingenuity Systems have extended their partnership to include the integration of Integromics' SeqSolve analysis software into Ingenuity's IPA software. The SeqSolve software is used with next-generation sequencing systems to perform tertiary level analysis of RNA-seq data at the gene and transcript level.

Source BioScience is providing its next-generation sequencing services to research teams at the Universities of Leicester and Nottingham for the Healthcare and Bioscience iNet. The partnership is aiming to identify common genetic variants associated with lung diseases.

Caliper Life Sciences announced this week that its Caliper Discovery Alliances and Services business has formed a collaboration with Denver-based health system Catholic Health Initiatives to develop improved methods for evaluating and predicting the efficacy of new cancer drugs. CDAS will perform biomarker and standard-of-care drug resistance/sensitivity studies on tumor samples provided by the health system.

CLC Bio has inked a contract to provide the Agricultural Research Council in South Africa with its enterprise bioinformatics platform across several geographic locations in the country. The ARC intends to use CLC Bio's platform and other next-generation sequencing technologies to study drought tolerance in crops using quantitative gene expression, map genome sequences for indigenous vegetable crops, and identify and characterize unknown pathogens from animals or plants.

The Ontario Genomics Institute said this week that it has launched a new website,, to demystify genetics and genomics and help the general public understand the importance of genetics research.

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.