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In Brief This Week: GenMark Diagnostics; Roche; Vermillion

By a GenomeWeb Staff Reporter

NEW YORK (GenomeWeb News) – GenMark Diagnostics said this week that it has received a medical device manufacturing license for its new Carlsbad, Calif., facility. The firm said that it can now manufacture and distribute all existing and future products from the facility. It also means that GenMark will cease all manufacturing and distribution from its Pasadena, Calif., facility as of the end of March 2011.

Roche this week said that it has acquired PVT Probenverteiltechnik of Waiblingen, Germany, and its US distributor PVT Lab Systems of Atlanta, for up to €85 million ($120.2 million). PVT makes customized automation and workflow solutions, such as pipettes and centrifuges, for in vitro diagnostic testing in commercial and hospital labs. Roche has agreed to pay PVT's shareholders €65 million up front, and another €20 million if certain milestones are met.

Vermillion said that its OVA1 multiplex, proteomic biomarker test, which is used to help physicians assess, prior to surgery, the likelihood that a woman's ovarian mass is malignant, has been included in the recent American College of Obstetricians and Gynecologists/Society of Gynecologic Oncologists committee opinion. The updated opinion cites US Food and Drug Administration clearance of the OVA1 test and indicates that the test "appears to improve the predictability of ovarian cancer in women with pelvic masses," the firm said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.