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In Brief This Week: Gen-Probe; Bio-Rad Laboratories; Becton Dickinson; Genewiz

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Gen-Probe disclosed in a quarterly filing with the US Securities and Exchange Commission this week that it had purchased around $4 million of Roka Bioscience's Series C preferred stock as part of Roka's recently completed $20 million financing round. Roka is a spinout of Gen-Probe to develop molecular assays for biopharmaceutical production, water and food safety testing, and other applications. Gen-Probe said in the filing that it now owns roughly 19 percent of Roka's stock on a fully diluted basis.

Bio-Rad Laboratories was sued this week by South Korean firm NanoEnTek and its subsidiary Digital-Bio Technology for allegedly infringing their US Patent No. 7,842,157, titled, "Method for Bonding Plastic Micro Chip." According to the complaint, filed in the US District Court for the Eastern District of Virginia, the plaintiffs allege that Bio-Rad's TC10 Automated Cell Counter and TC10 Counting Slides infringe their patent.

Becton Dickinson disclosed in a filing with the US Securities and Exchange Commission this week that it paid approximately $205 million for the acquisition of Accuri Cytometers in March.

Genewiz said this week that it has received Quality Management System certification from the International Organization for Standardization for its Suzhou, China operation. The firm provides DNA sequencing, gene synthesis, and other molecular biology services.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.