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In Brief This Week: Fluidigm; Artemis Health; Pacific Biomarkers

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Fluidigm said that it may become entitled to certain tax incentives for its business in Singapore, under a proposal from the Singapore Economic Development Board. The South San Francisco-based microfluidics and sample preparation technologies firm said that the tax incentives depend on the size and scope of its business in Singapore and its aggregate investments there. Fluidigm noted that affiliated entities of the Singapore EDB, BioMedical Sciences Investment Fund and Singapore Bio-Innovations, hold around 9 percent of the firm's capital stock.

Artemis Health has changed its name to Verinata Health. The San Carlos, Calif.-based firm is developing a non-invasive pre-natal diagnostic test to detect fetal chromosomal abnormalities, such as the one associated with Down syndrome. This week, Verinata published results of an initial validation study of a sequencing-based prenatal test to identify multiple fetal chromosomal abnormalities, including trisomy 21 and trisomy 18, in the journal Clinical Chemistry.

Pacific Biomarkers said this week that it has been awarded nine contracts by one unnamed sponsor to conduct biomarker services. The contracts have a total value of around $920,000, and the work will be conducted from 2011 to 2014.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.