NEW YORK (GenomeWeb News) – Exact Sciences said in its 10-K filing with the US Securities and Exchange Commission this week that in December it entered into an amendment to a licensing agreement pursuant to which Hologic granted the company a non-exclusive worldwide license to certain Hologic patents within the field of any disease or condition within, related to, or affecting the gastrointestinal tract and/or appended mucosal surfaces. The amendment is to an agreement the firms signed in 2009.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.